Nucleosomes

Nucleosomes are the basic repeating units of chromatin, consisting of a segment of DNA wound around a core of eight histone proteins. They play a crucial role in regulating gene expression and DNA replication by controlling access to the DNA. Nucleosomes can be modified by various chemical modifications, such as acetylation, methylation, and phosphorylation, which can affect the structure of chromatin and the accessibility of DNA to transcription factors and other proteins. These modifications can be heritable and can contribute to the regulation of gene expression over multiple generations. Nucleosomes are also involved in DNA repair and recombination, as well as in the maintenance of genome stability.

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Nucleosomes

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