ChIP
Chromatin immunoprecipitation (ChIP) is a technique used to study the interaction between proteins and DNA in the cell. It involves the cross-linking of proteins to DNA, followed by the isolation of the protein-DNA complex using an antibody specific to the protein of interest. The DNA is then purified and analyzed to identify the genomic regions that are bound by the protein. ChIP can be used to study a variety of protein-DNA interactions, including transcription factor binding, histone modifications, and DNA methylation. It is a powerful tool for understanding the regulation of gene expression and the epigenetic mechanisms that control cell fate and function.
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